‹ ›
MYP_172588
← PREVIOUS NEXT → BACK
Basic Information
AM-CATH36
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
36 amino acids
C194H337N57O38
Standard
Sequence
GLFKKLRRKIKKGFKKIFKRLPPIGVGVSIPLAGKR
Physicochemical Analysis
4076.11 Da
12.00
12.75
12.53
0.3542
-0.25
0.94
-0.14
29.96
105.56
0.0833
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1557.46
-8.32
56.0
51.0
145.0
289.0
6.0
35.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0116619 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
5.2 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0117472 VERIFIED: YES
Provenance & Taxonomy
Alligator mississippiensis [Animal]
cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
21 μg/mL
MIC
PMID34121235;28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34121235/
RECORD: Rec_0145194 VERIFIED: YES
Provenance & Taxonomy
American alligator [other]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli ATCC 4157
34 μM
MIC
PaperCathelicidin antimicrobial peptide from Alligator mississippiensis has antibacterial activity against multi-drug resistant Acinetobacter baumanii and Klebsiella pneumoniae.
RECORD: Rec_0165703 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
A549 human lung epithelial cells
Cell viability assay
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0177877 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
FIRST PREV 1 2 3 4 5 ... 8 NEXT LAST
Showing 5 records on this page · Page 3 of 8