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MYP_172565
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Anti-breast cancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ BChE Inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid agonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid antagonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Neurological / Signaling ▸ Neuroactive peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C30H37N5O7
Standard
Sequence
YPFPG
Physicochemical Analysis
579.64 Da
5.52
-0.24
-0.45
-0.0482
-0.42
0.09
0.43
109.72
0.00
0.4000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
182.37
0.17
5.0
7.0
11.0
42.0
4.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009344 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory
Mice
PaperConsumption of β-casomorphins-7/5 induce inflammatory immune response in mice gut through Th-2 pathway | Ul Haq, MR. et al. | DOI: 10.1016/j.jff.2014.03.018 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0078344 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid receptor ligand Opioid agonist
PaperContents of agonistic and antagonistic opioid peptides in different cheese varieties | Sienkiewicz-Szłapka, E. et al. | DOI: 10.1016/j.idairyj.2008.10.011 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0079491 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Opioid peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
RECORD: Rec_0084614 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Agonist
opioid receptor
1.1
PaperHenschen A., Lottspeich F., Brantl V., Teschemacher H.. Novel opioid peptides derived from casein (beta-casomorphins). II. Structure of active components from bovine casein peptone. Hoppe-Seyler's Z. Physiol. Chem., 360, 1217-1224, 1979.
RECORD: Rec_0085704 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
myenteric plexus of guinea pig ileum longitudianal muscle
0.69 μM
IC50
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