Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length508 amino acids

Chemical FormulaC2590H4044N650O735S19

DescriptionStandard

        MCTKMAHVQVLWGCFLLWNLHISSAQAIYPGIKARATQRALDYAVQAGMEMIEQMAKERKIPDLKGSESLEFLKIDYVNYNFTNIKINAFSFPNTSLAFVPGVGIRALTNHGTTNISTDWEVKSPLFQDTGAADLFLSGVYFTGIVVLSRNDLGHPILKLQDCYAQVSHADVSFSGELSVLYNSFAEPMEKPILKKLNEMLCPIITGEVEALNTNLSMLEVLRKIDNYTLLDYSLISSPEITENYFDLNLKGVFYPLKSLQYPPFPSVPFVLPERSDSMLYIGISKYFFKSASYAYFTAGAFSFTLTTKEISNHLLHNSQALGNMLSRIAELYILSQPFMVQVMATEPPVISLLPGNFTLDIPASIMILTQPKNSTAEAIVSMDFVASTNVALAILGQRLICSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISLVNSDIEVLEGFLLISTDLKYKTSKQQPGFHGWEGLHLISGQWSRKPIP
    

Molecular Weight56656.96 Da

Isoelectric Point (pI)6.28

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -4.51

Charge Density (pH 7.0) -0.0070

GRAVY Index0.13

Hydrophobic Moment 0.68

Boman Index0.16

Instability Index39.28

Aliphatic Index 103.09

Aromaticity 0.1024

Extinction Coeff. Reduced 54320.00

Extinction Coeff. Oxidized 54570.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0287744 VERIFIED: NO

Provenance & Taxonomy

OrganismMoschus moschiferus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence