MYP_172537
Panitide L1
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Standard
28 amino acids
C130H210N36O38S6
Standard
QLPICGETCVLGTCYTPGCRCQYPICVR
3077.67 Da
7.77
0.70
0.41
0.0251
0.35
0.40
0.12
1.40
76.43
0.0714
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1171.08
-12.06
46.0
45.0
92.0
210.0
5.0
29.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0008158
VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial
Antibacterial
Cytotoxic
Anti-Gram-negative
Escherichia coli
RECORD: Rec_0281101
VERIFIED: YES
Provenance & Taxonomy
Steinchisma laxum [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0324879
VERIFIED: YES
Provenance & Taxonomy
Panicum laxum [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
N-terminal pyroglutamate
Bio-Activity Profile
Antimicrobial
Cytotoxic
HeLa cells