Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC362H594N104O93S8

DescriptionStandard

        MRVLHSILGVLALLSIVPQARTLFVKYTCSLEAYNCRMKCNADEHAIRYCADWTICCKGRKTKLQKKKKW
    

Molecular Weight8147.75 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)9.61

Net Charge (pH 7.4) 9.18

Charge Density (pH 7.0) 0.1373

GRAVY Index-0.11

Hydrophobic Moment 0.57

Boman Index-0.06

Instability Index9.29

Aliphatic Index 92.00

Aromaticity 0.0857

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3218.91

LogP -25.59

H-bond Donors 122.0

H-bond Acceptors 113.0

Rotatable Bonds 277.0

Heavy Atoms 567.0

Ring Count 11.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161188 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0319950 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence