Peptide Database

Peptide NameMaximins 1 H12 [Cleaved into: Maximin-1; Maximin-H12]

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antiviral

Antiviral ▸ Anti-HIV

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Reproductive biology ▸ Contraceptive activity ▸ Spermicidal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC704H1155N197O226S3

DescriptionStandard

        MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGVKTALKGALKELASTYANGKRTAEEHEVMKRLEVVMRDLDSLDYPEEASERETRDFNQEEIANLYTKKEKRLLGPVLGLVSNALGGLLKNIG
    

Molecular Weight16091.08 Da

Isoelectric Point (pI)5.22

Net Charge (pH 7.0)-4.37

Net Charge (pH 7.4) -4.69

Charge Density (pH 7.0) -0.0303

GRAVY Index-0.44

Hydrophobic Moment 0.71

Boman Index-0.09

Instability Index50.08

Aliphatic Index 96.88

Aromaticity 0.0556

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6929.17

LogP -68.82

H-bond Donors 241.0

H-bond Acceptors 226.0

Rotatable Bonds 565.0

Heavy Atoms 1130.0

Ring Count 11.0

Amide Bonds 153.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250660 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin; Maximin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Antiviral Anti-HIV Anti-Candida Cytolytic Cytotoxic Hemolytic Spermicidal

TargetNo Target Organism Found