Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2303H3619N609O641S9

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIAILEKELAQLTLPDISGDFRVLRVGKVHYELSRLRLRSFHLPYSRISPVPNVGLQVSISNAFAEMDGDWRVKVLFIRDHGSFDLKVENVYIKISLRLGSDAAGKPTISTSDCSTRISKVRVLFSGKFGWLYNLFHSAIESKFKKILESKVCDSVAKSVHSELQTYARTLPVTAKIDARTGIDYSFVAPPVATAQSLDTGLKGEFYSLAHRSTAPFSPMPLSLPSDHDRMVSFGASSYFFNTAGFAYHTSGALVFEITDAVIPKDVDFHLNTSIFSAFVPQLEQMYPNMPMKLRLSTLTAPFLNIGPGGISLKPVVDVQAYAILPDSSLAPLFLLSLVRNVSAVIDVRSGHIVGSLNVGRIKLSLKDSVVGTFPVRLLQSLMNIFASEVLLPRLNARLDEGFPLPLPDRIQLFNTFVRFHQNFLLLGADVHFQPK
    

Molecular Weight50382.65 Da

Isoelectric Point (pI)9.31

Net Charge (pH 7.0)8.54

Net Charge (pH 7.4) 7.58

Charge Density (pH 7.0) 0.0187

GRAVY Index0.14

Hydrophobic Moment 0.69

Boman Index0.12

Instability Index38.54

Aliphatic Index 102.59

Aromaticity 0.0987

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095965 VERIFIED: NO

Provenance & Taxonomy

OrganismOxyruncus cristatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria