Peptide Database

Peptide NameBeta-defensin 129

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC893H1455N241O269S13

DescriptionStandard

        MKLLFPIFASLMLQYQVNTEFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPKVVKLIKNYLQYGTPNVLNEDVQEMLKPAKNSSAVIQRKHILSVLPQIKSTSFFANTNFVIIPNATPMNSATISTMTPGQITYTATSTKSNTKESRDSATASSPPAPPPPNILPTPSLELEEAEEQ
    

Molecular Weight20288.40 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)5.63

Net Charge (pH 7.4) 5.18

Charge Density (pH 7.0) 0.0308

GRAVY Index-0.28

Hydrophobic Moment 0.72

Boman Index-0.00

Instability Index45.11

Aliphatic Index 81.53

Aromaticity 0.0546

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8190.15

LogP -103.32

H-bond Donors 279.0

H-bond Acceptors 290.0

Rotatable Bonds 672.0

Heavy Atoms 1416.0

Ring Count 28.0

Amide Bonds 203.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118033 VERIFIED: NO

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyDefensin

Tax ID9595

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence