Peptide Database

Peptide NameSLAY-screened peptide P5067

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC74H117N21O23S

DescriptionStandard

        SNREGVGWSCLPVSPL
    

Molecular Weight1700.91 Da

Isoelectric Point (pI)5.72

Net Charge (pH 7.0)-0.55

Net Charge (pH 7.4) -0.77

Charge Density (pH 7.0) -0.0342

GRAVY Index-0.02

Hydrophobic Moment 0.20

Boman Index0.12

Instability Index95.73

Aliphatic Index 85.00

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 701.01

LogP -8.02

H-bond Donors 25.0

H-bond Acceptors 24.0

Rotatable Bonds 50.0

Heavy Atoms 119.0

Ring Count 4.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068214 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/