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MYP_172425
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Basic Information
MBjAMP-re
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C104H179N41O26S2
Standard
Sequence
NLCASLRARHTIPQCRKFGRR
Physicochemical Analysis
2483.92 Da
11.83
5.83
5.54
0.2774
-0.79
0.64
-0.44
55.76
65.24
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1127.37
-13.56
44.0
35.0
83.0
173.0
3.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006428 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
multidrug-resistant Pseudomonas aeruginosa CCARM 2095
50 μM
MIC
PMID30475621 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30475621/
RECORD: Rec_0015944 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
12.5 μM
MIC
PMID30475621 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30475621/
RECORD: Rec_0041783 VERIFIED: YES
Provenance & Taxonomy
Branchiostoma floridae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0060020 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
12.5 μM
MIC
PMID30475621 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30475621/
RECORD: Rec_0071389 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
multidrug-resistant Pseudomonas aeruginosa CCARM 2095
50 μM
MIC
PMID30475621 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30475621/
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