Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 6.11

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC198H302N64O60S9

DescriptionStandard

        VHTNIPCRGTSDCYEPCEKKYNCARAKCMNRHCNCYNNCPW
    

Molecular Weight4827.49 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)2.83

Net Charge (pH 7.4) 2.39

Charge Density (pH 7.0) 0.0690

GRAVY Index-1.00

Hydrophobic Moment 0.51

Boman Index-0.27

Instability Index23.84

Aliphatic Index 21.46

Aromaticity 0.0976

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2029.68

LogP -25.24

H-bond Donors 77.0

H-bond Acceptors 74.0

Rotatable Bonds 151.0

Heavy Atoms 331.0

Ring Count 10.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411575 VERIFIED: YES

Provenance & Taxonomy

OrganismOpisthacanthus madagascariensis [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-28; 13-33; 17-35; 23-39

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense