Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC205H329N53O60S

DescriptionStandard

        MLAVIGAVTVALSGGIDAILEVGWTAFIAEVKEQAAARGTAGAAAW
    

Molecular Weight4528.19 Da

Isoelectric Point (pI)4.41

Net Charge (pH 7.0)-2.49

Net Charge (pH 7.4) -2.71

Charge Density (pH 7.0) -0.0542

GRAVY Index0.99

Hydrophobic Moment 0.45

Boman Index0.44

Instability Index6.71

Aliphatic Index 119.13

Aromaticity 0.0652

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1765.53

LogP -14.83

H-bond Donors 62.0

H-bond Acceptors 59.0

Rotatable Bonds 145.0

Heavy Atoms 319.0

Ring Count 5.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008390 VERIFIED: NO

Provenance & Taxonomy

OrganismEnterococcus villorum [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal