Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length115 amino acids

Chemical FormulaC546H889N151O165S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASISLLPGSGIKLVIGNASLTIDMNWNIRTWMLKDSGRGTVHISKVFVTAIFSTPLHNTCPTSSISLTSCRTTSGDIDIKLNGKT
    

Molecular Weight12337.07 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)4.29

Net Charge (pH 7.4) 3.98

Charge Density (pH 7.0) 0.0373

GRAVY Index0.06

Hydrophobic Moment 0.54

Boman Index0.12

Instability Index25.96

Aliphatic Index 99.13

Aromaticity 0.0522

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5036.78

LogP -57.46

H-bond Donors 181.0

H-bond Acceptors 177.0

Rotatable Bonds 407.0

Heavy Atoms 866.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0066322 VERIFIED: NO

Provenance & Taxonomy

OrganismPycnonotus jocosus (Red-whiskered bulbul) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria