Peptide Database

Peptide NameTaliglucerase alfa

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC246H367N67O74S4

DescriptionStandard

        EFARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRR
    

Molecular Weight5575.21 Da

Isoelectric Point (pI)8.52

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.0360

GRAVY Index-0.30

Hydrophobic Moment 0.38

Boman Index-0.04

Instability Index62.11

Aliphatic Index 39.00

Aromaticity 0.1600

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2256.30

LogP -27.05

H-bond Donors 85.0

H-bond Acceptors 80.0

Rotatable Bonds 168.0

Heavy Atoms 391.0

Ring Count 13.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037662 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEnzyme

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme replacement

Half-Lifebetween 18.9 to 28.7 min.