Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length338 amino acids

Chemical FormulaC1688H2619N467O469S8

DescriptionStandard

        RLNLRSFHLPYSRISLVPNVGLQVSISNAFAEVDGNWRVKIHFIRDHGSFDLKVENIYIKINLRLGSDTSGKPTIDTSDCSTRISKVRVHFSGKFGWLYNLFHSAIESRFRKTLESKVCDSVDSSVRGDLQPYLQTLPVTARIDATSGIDYSLVAPPAATAQSLDVKLKGEFFSLAHRSAVPFPPLALAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEVTDSMIPKGIDFHLNTSTFSAFIPQLEKMYPERLMKLRLPPPSQPSFPRFNAASKRAPGWAAALRLVGAVPPGARFGVRWGEPCRSSALSPQTCNVSAVIDVRSGHIVGSLKVGR
    

Molecular Weight37215.22 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)13.61

Net Charge (pH 7.4) 12.78

Charge Density (pH 7.0) 0.0403

GRAVY Index-0.06

Hydrophobic Moment 0.65

Boman Index0.06

Instability Index41.96

Aliphatic Index 85.41

Aromaticity 0.1065

Extinction Coeff. Reduced 35410.00

Extinction Coeff. Oxidized 35660.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255275 VERIFIED: NO

Provenance & Taxonomy

OrganismPodiceps cristatus [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria