Peptide Database

Peptide NamegcDefb1

Function Ontology

Antimicrobial

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC318H501N81O86S8

DescriptionStandard

        MKPQSILVLLVLAVLALHCKENEAASFPWTCASLSGVCRQGVCLPSELYFGSLGCGKGFLCCVSHFG
    

Molecular Weight7091.39 Da

Isoelectric Point (pI)7.57

Net Charge (pH 7.0)0.61

Net Charge (pH 7.4) 0.18

Charge Density (pH 7.0) 0.0091

GRAVY Index0.77

Hydrophobic Moment 0.44

Boman Index0.31

Instability Index30.40

Aliphatic Index 103.28

Aromaticity 0.0896

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2593.90

LogP -22.26

H-bond Donors 96.0

H-bond Acceptors 97.0

Rotatable Bonds 227.0

Heavy Atoms 493.0

Ring Count 12.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344645 VERIFIED: YES

Provenance & Taxonomy

OrganismCtenopharyngodon idella [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-inflammatory

Targeted the growth of Aeromonas hydrophila ATCC 7966

Activity36 μM

MethodMIC

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