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MYP_172249
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Basic Information
AM-CATH21
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C127H222N38O22
Standard
Sequence
GLFKKLRRKIKKGFKKIFKRL
Physicochemical Analysis
2633.36 Da
12.00
10.75
10.54
0.5120
-0.80
0.94
-0.43
19.81
92.86
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1039.18
-3.86
39.0
33.0
101.0
187.0
3.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0235814 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0247371 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 9027
10 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0248310 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
A549 human lung epithelial cells
Cell viability assay
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0254604 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 33592
28 μg/mL
MIC
PMID28089718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28089718/
RECORD: Rec_0260958 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
E-faecalis ATCC 22192 or 51299
>16 μM
MIC
PaperCathelicidin antimicrobial peptide from Alligator mississippiensis has antibacterial activity against multi-drug resistant Acinetobacter baumanii and Klebsiella pneumoniae.
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