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MYP_172246
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Basic Information
Alpha-basrubrin
Anticancer
Antimicrobial
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Antiviral
Antiviral ▸ Anti-HIV
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
20 amino acids
C96H145N33O33S2
Standard
Sequence
GADFQECMKEHSQKQHQHQG
Physicochemical Analysis
2353.51 Da
6.27
-0.98
-1.36
-0.0492
-1.90
0.44
-0.37
62.82
5.00
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1101.88
-14.50
36.0
37.0
83.0
164.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0204355 VERIFIED: NO
Provenance & Taxonomy
Basella alba [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Fungicide Antiviral Anti-HIV Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID11688973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11688973/; https://www.uniprot.org/uniprotkb/P83186/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0290481 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0304486 VERIFIED: YES
Provenance & Taxonomy
Basella alba [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
M. arachidicola
PMID11688973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11688973/
RECORD: Rec_0336591 VERIFIED: YES
Provenance & Taxonomy
Basella alba [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
Botrytis cinerea
PaperPubMed PMID: 11688973 PMID11688973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11688973/
RECORD: Rec_0357389 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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