Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC911H1440N252O284S3

DescriptionStandard

        MGGVPAQTILINSVPTGPAAPSHTGNGSSVPKTPVNTGTNVRQADSIVVTTFPADVVQDLQDFILWQPDATETGVEALYVMVSDPLDSGRFTRKQLDKKFKHASDFGIADTKKNSVTLTQYRHAIEAHLKDKNTVEKGTYRREKESKVYFNPKNMGVVIIKANGDFLSGWKINPDADNGRIYLETGDL
    

Molecular Weight20562.89 Da

Isoelectric Point (pI)6.91

Net Charge (pH 7.0)-0.13

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0007

GRAVY Index-0.47

Hydrophobic Moment 0.59

Boman Index-0.02

Instability Index21.84

Aliphatic Index 76.70

Aromaticity 0.0745

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8642.04

LogP -108.72

H-bond Donors 293.0

H-bond Acceptors 291.0

Rotatable Bonds 678.0

Heavy Atoms 1450.0

Ring Count 31.0

Amide Bonds 205.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062655 VERIFIED: YES

Provenance & Taxonomy

OrganismSerratia liquefaciens [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)