Peptide Database

Peptide NameGnRH

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC41H59N11O15

DescriptionStandard

        EHSYGLSPG
    

Molecular Weight945.97 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.08

Net Charge (pH 7.4) -1.30

Charge Density (pH 7.0) -0.1197

GRAVY Index-0.91

Hydrophobic Moment 0.13

Boman Index0.10

Instability Index39.90

Aliphatic Index 43.33

Aromaticity 0.1111

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 414.00

LogP -5.14

H-bond Donors 14.0

H-bond Acceptors 15.0

Rotatable Bonds 27.0

Heavy Atoms 67.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0128870 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGnRH

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide

RECORD: Rec_0327946 VERIFIED: YES

Provenance & Taxonomy

OrganismPiaractus mesopotamicus [Animal]

FamilyGnRH

Tax ID42528

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other Mods10:Glycine amide

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0413783 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/