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MYP_172184
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Renin inhibition ▸ Renin inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
2 amino acids
C12H16N2O4
Standard
Sequence
SF
Physicochemical Analysis
252.27 Da
5.24
-0.54
-0.75
-0.2700
1.00
0.62
0.51
5.00
0.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
112.65
-0.88
4.0
4.0
6.0
18.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0103589 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
ACE-inhibitory peptide
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAnimal and Plant Proteins as Precursors of Peptides with ACE Inhibitory Activity – An in silico Strategy of Protein Evaluation
RECORD: Rec_0137097 VERIFIED: NO
Provenance & Taxonomy
Triticum aestivum [Plant]
ACE-inhibitory peptide
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperMOTIFS WITH POTENTIAL PHYSIOLOGICAL ACTIVITY IN FOOD PROTEINS - BIOPEP DATABASE
RECORD: Rec_0149142 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive Renin inhibitory
Renin
PaperUdenigwe C.; Li H.; Aluko R.. Quantitative structure-activity relationship modeling of renin-inhibiting dipeptides. Amino Acids, 42, 1379-1386, 2012.
RECORD: Rec_0209436 VERIFIED: NO
Provenance & Taxonomy
Allium sativum [Plant]
ACE-inhibitory peptide
4682
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory Antioxidant
ACE
130.2 μM
IC50
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0213781 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
3.89 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
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