Peptide Database

Peptide NameLipopolysaccharide-binding protein (LBP)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length481 amino acids

Chemical FormulaC2404H3810N632O686S16

DescriptionStandard

        MKAGTGPLLSTLLGLLFLSIQGTGGVNPGVVARITDKGLAYAAKEGLVALQRELYKITLPDFSGDFKIKAVGRGQYEFHSLEIQNCELRGSSLKLLPGQGLSLAISDSSIGVRGKWKVRKSFLKLHGSFDLDVKGVTISVDLLLGMDPSGRPTVSASGCSSRICDLDVHISGNVGWLLNLFHNQIESKLQKVLENKVCEMIQKSVTSDLQPYLQTLPVTAEIDNVLGIDYSLVAAPQAKAQVLDVMFKGEIFNRNHRSPVATPTPTMSLPEDSKQMVYFAISDYAFNIASRVYHQAGYLNFSITDDMLPHDSGIRLNTKAFRPFTPQIYKKYPDMKLELLGTVVSAPILNVSPGNLSLAPQMEIEGFVILPTSAREPVFRLGVVTNVFASLTFNNSKVTGMLHPDKAQVRLIESKVGMFNVNLFQAFLNYYLLNSLYPDVNAELAQGFPLPLPRHIQLHDLDFQIRKDFLYLGANVQYMRV
    

Molecular Weight53054.83 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)4.37

Net Charge (pH 7.4) 3.48

Charge Density (pH 7.0) 0.0091

GRAVY Index0.05

Hydrophobic Moment 0.73

Boman Index0.12

Instability Index32.98

Aliphatic Index 102.52

Aromaticity 0.0873

Extinction Coeff. Reduced 34840.00

Extinction Coeff. Oxidized 35090.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0292142 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBPI/LBP

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Anti-Gram-negative Non-hemolytic

TargetGram Negative Bacteria

PaperLineage-specific biology revealed by a finished genome assembly of the mouse; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID9144073;19468303;15489334;24380872;24120359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9144073/