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MYP_172133
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Basic Information
Aurein-2.2 (1-14)[V10L, G11K, A12L, G14K]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C79H140N18O17
Standard
Sequence
GLFDIVKKVLKLLK
Physicochemical Analysis
1614.07 Da
10.00
2.76
2.55
0.1969
0.81
0.82
0.18
-14.28
180.71
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
583.00
0.11
20.0
20.0
59.0
114.0
1.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0099342 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 90028
20 μM
MIC
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
RECORD: Rec_0152949 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii ATCC 19606
20 μM
MIC
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
RECORD: Rec_0254529 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30506920 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30506920/
RECORD: Rec_0281675 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human breast adenocarcinoma MCF-7
12
EC50
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
RECORD: Rec_0282735 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Cryptococcus neoformans ATCC 208821
20 μM
MIC
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
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