‹ ›
MYP_172133
← PREVIOUS NEXT → BACK
Basic Information
Aurein-2.2 (1-14)[V10L, G11K, A12L, G14K]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C79H140N18O17
Standard
Sequence
GLFDIVKKVLKLLK
Physicochemical Analysis
1614.07 Da
10.00
2.76
2.55
0.1969
0.81
0.82
0.18
-14.28
180.71
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
583.00
0.11
20.0
20.0
59.0
114.0
1.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0009873 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
8 μM
Hemolysis
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
RECORD: Rec_0041178 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30506920 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30506920/
RECORD: Rec_0059967 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus SH1000
3.3 μM
MIC
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
RECORD: Rec_0061236 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
20 μM
MIC
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
RECORD: Rec_0061578 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Aurein
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
20 μM
MIC
PMID32936629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32936629/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3