Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length137 amino acids

Chemical FormulaC683H1069N177O197S13

DescriptionStandard

        MRVLLSILGTLTLLSLVLQAQSSIYTQGCPPGNYKCRLQCNPNEYAIRYCGDWSICCKVKRSETMKKNFLELNESFSVAYSGYLFKCSCDAITKKWKPSKCPLADEWIKKLWVGGIGVCDQEGGFTQNFGGECGIEL
    

Molecular Weight15328.71 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)3.40

Net Charge (pH 7.4) 2.98

Charge Density (pH 7.0) 0.0248

GRAVY Index-0.10

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index37.80

Aliphatic Index 81.82

Aromaticity 0.1095

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 31565.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6029.94

LogP -55.84

H-bond Donors 219.0

H-bond Acceptors 214.0

Rotatable Bonds 510.0

Heavy Atoms 1070.0

Ring Count 24.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269130 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic