Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC928H1403N205O281S10

DescriptionStandard

        IDDLAEVDYSLNSLPAVFQPYIDLDLKGIIFPAGNYIGSPYMAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEVPVISLEQDSFTAEIQGFMEVLAVLPDSTTQLLFTMNVAANSSISLNIFDQKLMGSLCLNR
    

Molecular Weight20247.92 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.24

Net Charge (pH 7.4) -15.51

Charge Density (pH 7.0) -0.0833

GRAVY Index0.36

Hydrophobic Moment 0.55

Boman Index0.27

Instability Index46.14

Aliphatic Index 94.92

Aromaticity 0.1366

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7670.82

LogP -78.94

H-bond Donors 259.0

H-bond Acceptors 276.0

Rotatable Bonds 644.0

Heavy Atoms 1424.0

Ring Count 36.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371541 VERIFIED: NO

Provenance & Taxonomy

OrganismXiphorhynchus elegans [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria