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MYP_172117
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Basic Information
PV3 (Derived from pEM-2 and MP-VT1)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C89H163N25O15
Standard
Sequence
KKWRKLLKKLKKLL
Physicochemical Analysis
1823.40 Da
11.47
7.75
7.54
0.5538
-0.98
0.87
-0.49
-21.04
139.29
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
701.45
-0.18
26.0
23.0
71.0
129.0
2.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0230113 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
MDR Pseudomonas aeruginosa
PMID29327480 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29327480/
RECORD: Rec_0271487 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
HEK293 cells
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0315174 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0358979 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative bacteria: Pseudomonas aeruginosa isolates
1.0±0.0 μg/mL
MIC
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
RECORD: Rec_0391220 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii isolates
1.0±0.0 μg/mL
MIC
PMID27591703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27591703/
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