Peptide Database

Peptide NameBeta-defensin 131B (Defensin; beta 131)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC364H562N96O101S8

DescriptionStandard

        MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLKIIQIDGQKKW
    

Molecular Weight8155.46 Da

Isoelectric Point (pI)8.26

Net Charge (pH 7.0)1.62

Net Charge (pH 7.4) 1.20

Charge Density (pH 7.0) 0.0231

GRAVY Index-0.05

Hydrophobic Moment 0.52

Boman Index0.02

Instability Index34.39

Aliphatic Index 76.57

Aromaticity 0.1286

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3171.92

LogP -26.86

H-bond Donors 117.0

H-bond Acceptors 113.0

Rotatable Bonds 266.0

Heavy Atoms 569.0

Ring Count 15.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256569 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic

RECORD: Rec_0278775 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence