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MYP_172086
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Basic Information
Unnamed
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Standard
20 amino acids
C103H191N41O25
Standard
Sequence
KSVRGKGKGQKRKRKKSRYK
Physicochemical Analysis
2403.88 Da
12.00
11.75
11.53
0.5876
-2.63
0.42
-1.03
26.73
14.50
0.0500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1175.76
-14.56
45.0
37.0
95.0
169.0
1.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002864 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic
PaperAntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides PMID26335203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26335203/
RECORD: Rec_0026933 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic Anticancer VEGF-binding inhibitor
VEGF165 binding to human liposarcoma cells; ASPC-1 cells; HUVECs
>99; >99; 96 % inhibition
Flow cytometry VEGF165 cell-surface binding inhibition (10 μg/mL peptide)
PaperHSPG-Binding Peptide Corresponding to the Exon 6a-Encoded Domain of VEGF Inhibits Tumor Growth by Blocking Angiogenesis in Murine Model PMID20376344
RECORD: Rec_0334540 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
VEGF exon 6a
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-angiogenic
PaperAnti-angiogenic peptides for cancer therapeutics PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0335193 VERIFIED: NO
Provenance & Taxonomy
Exon 6a of VEGF gene [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
RECORD: Rec_0396544 VERIFIED: NO
Provenance & Taxonomy
Exon 6a of VEGF gene [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID21470139 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21470139/
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