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MYP_172074
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Basic Information
Stimulating vasoactive substance release
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor Of Cytosol Alanyl Aminopeptidase
Hormonal / Endocrine ▸ Hormone peptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Regulatory peptide ▸ Stimulation activity
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
3 amino acids
C18H35N3O4
Standard
Sequence
LLL
Physicochemical Analysis
357.49 Da
5.53
-0.24
-0.44
-0.0800
3.80
0.23
1.06
6.67
390.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
121.52
1.51
4.0
4.0
11.0
25.0
0.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0279163 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
2.3 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
RECORD: Rec_0329242 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 2-[(3S)-2,3-dihydro-3-methyl-1-oxo-4(1H)-isoquinolinylidene]-, methyl ester, (2Z)-acetic acid
Bio-Activity Profile
-
PaperAdvanced Synthesis & Catalysis Evidence URLhttps://doi.org/10.1002/1615-4169(200209
RECORD: Rec_0351334 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Inhibitor Of Cytosol Alanyl Aminopeptidase
Cytosol alanyl aminopeptidase
PaperGarner C.W., Behal F. J.. Human liver alanine aminopeptidase. Inhibition by amino acids. Biochemistry, 14, 3208-3212, 1975.
RECORD: Rec_0400931 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1.35 pIC50
pIC50
PaperQSAR study on angiotensin-converting enzyme inhibitor oligopeptides based on a novel set of sequence information descriptors. PMID20941517 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20941517/
RECORD: Rec_0415656 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
3847
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Enzyme inhibitory Taste ACE inhibitory
Angiotensin-I converting enzyme
22 μM
IC50
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