Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC791H1193N177O240S8

DescriptionStandard

        QGIVYPGGNYSAPPFVAAPFTVPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNITITEETCSYFNISTEIFSSVIPEVAQYSVTPYPVMLKLMATEIPIISLQQDSFTIEIQGSMEVFAVLPDSSTQLLFTMSIAANTSIAVNIFDQKLMGSLCLNR
    

Molecular Weight17278.49 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-10.24

Net Charge (pH 7.4) -10.51

Charge Density (pH 7.0) -0.0652

GRAVY Index0.37

Hydrophobic Moment 0.48

Boman Index0.28

Instability Index57.97

Aliphatic Index 88.85

Aromaticity 0.1401

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6589.64

LogP -60.82

H-bond Donors 224.0

H-bond Acceptors 238.0

Rotatable Bonds 544.0

Heavy Atoms 1216.0

Ring Count 32.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198327 VERIFIED: NO

Provenance & Taxonomy

OrganismCrypturellus undulatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria