Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length115 amino acids

Chemical FormulaC559H914N150O156S8

DescriptionStandard

        MEQADVLVPKGSLATQLPFSPRLRRVTLPGTEAASLLIMVTRSVLLGLAVLVLLSYVPPGSSGPNAYIQKAFASCWRLHGTCRSKCLKNEEYHILCDTTYLCCASPKQLPILTGK
    

Molecular Weight12488.67 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.19

Charge Density (pH 7.0) 0.0489

GRAVY Index0.25

Hydrophobic Moment 0.63

Boman Index0.13

Instability Index59.81

Aliphatic Index 106.00

Aromaticity 0.0609

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4829.68

LogP -44.31

H-bond Donors 174.0

H-bond Acceptors 172.0

Rotatable Bonds 402.0

Heavy Atoms 873.0

Ring Count 19.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140097 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyDefensin

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence