Peptide Database

Peptide NameB4

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC78H135N17O14

DescriptionStandard

        LKKLFKKILKYL
    

Molecular Weight1535.01 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)4.75

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.3962

GRAVY Index0.14

Hydrophobic Moment 0.83

Boman Index-0.04

Instability Index-15.61

Aliphatic Index 162.50

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 533.75

LogP 1.80

H-bond Donors 19.0

H-bond Acceptors 19.0

Rotatable Bonds 57.0

Heavy Atoms 109.0

Ring Count 2.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389529 VERIFIED: YES

Provenance & Taxonomy

Organismantimicrobial peptides [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetMCF-7

Activity5.9±0.2 μM

MethodIC50

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