MYP_171944
SPMI2
Anticancer
Standard
11 amino acids
C65H93N15O18
Standard
TSFREYWALLS
1372.52 Da
5.66
-0.60
-0.79
-0.0545
-0.03
0.38
0.12
-14.00
80.00
0.2727
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
550.23
-3.23
21.0
18.0
41.0
98.0
4.0
10.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0088803
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
MDM2/MDMX-binding peptide
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Stapled: Ⓧ(4) and Ⓧ (11) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
HCT116 p53-/-
>100 μM
IC50
RECORD: Rec_0269423
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
MDM2/MDMX-binding peptide
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Acetylation
Amidation
Stapled: Ⓧ(4) and Ⓧ (11) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
HCT116 p53+/+
28.4 μM
IC50