Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC97H158N30O36S5

DescriptionStandard

        GIVDQCCTNICSRNQLMSYCND
    

Molecular Weight2480.80 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-1.28

Net Charge (pH 7.4) -1.54

Charge Density (pH 7.0) -0.0580

GRAVY Index-0.19

Hydrophobic Moment 0.41

Boman Index-0.06

Instability Index50.44

Aliphatic Index 66.36

Aromaticity 0.0455

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1107.29

LogP -15.84

H-bond Donors 41.0

H-bond Acceptors 40.0

Rotatable Bonds 82.0

Heavy Atoms 168.0

Ring Count 1.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037238 VERIFIED: YES

Provenance & Taxonomy

OrganismMyocastor coypus [Animal]

FamilyInsulin

Tax ID10157

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour