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MYP_171903
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Basic Information
DEFB120
Antimicrobial
Antimicrobial ▸ Antifungal
Standard
29 amino acids
C139H232N50O42S7
Standard
Sequence
ECWMDGHCRLLCKDGEDSIIRCRNRKRCC
Physicochemical Analysis
3500.09 Da
8.37
1.87
1.55
0.0644
-0.81
0.57
-0.42
67.32
53.79
0.0345
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1533.95
-16.96
62.0
52.0
121.0
238.0
3.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066794 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0209289 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0226786 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperProduction and characterization of recombinant human beta-defensin DEFB120.