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MYP_171855
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
34 amino acids
C155H255N43O43S2
Standard
Sequence
ALWFTMLKKLGTMALHAGKAALGAAANTISQGTQ
Physicochemical Analysis
3473.08 Da
10.30
2.88
2.64
0.0847
0.38
0.46
0.27
6.27
92.35
0.0588
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1376.57
-13.89
48.0
49.0
116.0
243.0
4.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0163158 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Antiparasitic
A. caviae
30 μg/mL
MIC
PaperThe Vertebrate Peptide Antibiotics Dermaseptins Have Overlapping Structural Features but Target Specific Microorganisms
RECORD: Rec_0189576 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
70 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/7989335/ PMID7989335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7989335/
RECORD: Rec_0190470 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagei [Animal]
Dermaseptin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiprotozoal
Aspergillus fumigatus
PaperPubMed PMID: 8306981 PMID8306981 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8306981/
RECORD: Rec_0197203 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
A.fumigatus
PMID8306981 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8306981/
RECORD: Rec_0216378 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa sauvagii [Animal]
Dermaseptin
8395
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiviral Antiparasitic
A. niger IP218-53 and A. fumigatus IP1025-70
20 μM
MIC
PaperThe Vertebrate Peptide Antibiotics Dermaseptins Have Overlapping Structural Features but Target Specific Microorganisms
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