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MYP_171847
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Basic Information
Angiotensin I-converting enzyme inhibitory peptide 4
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
8 amino acids
C38H60N10O14
Standard
Sequence
YETGNGIK
Physicochemical Analysis
880.94 Da
6.00
-0.24
-0.45
-0.0299
-1.15
0.39
-0.06
-61.91
48.75
0.1250
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
413.89
-4.70
14.0
14.0
29.0
62.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070265 VERIFIED: YES
Provenance & Taxonomy
Schistocerca gregaria [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
lipase
94.91 ± 0.1 μg/mL
IC50
RECORD: Rec_0140831 VERIFIED: YES
Provenance & Taxonomy
Tenebrio molitor [Animal]
7067.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperZieli¨½ska E., Baraniak B., Kara? M.. Identification of antioxidant and anti-inflammatory peptides obtained by simulated gastrointestinal digestion of three edible insects species (Gryllodes sigillatus, Tenebrio molitor, Schistocerca gragaria). Int. J. Food Sci. Technol., 53, 2542-2551,.
RECORD: Rec_0144146 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Metabolic Syndrome Pancreatic lipase inhibitory
Pancreatic lipase
107.8
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0207912 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
3.69
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0340705 VERIFIED: YES
Provenance & Taxonomy
Schistocerca gregaria [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
3.25 ± 0.09 μg/mL
IC50