Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC374H613N95O99S8

DescriptionStandard

        MRSLLSVLVILVLLSYVPPGKMEFPSIYSTCWRLKGVCKRTCAKKEVYHILCDTATLCCISAKDLPPLVSRSSF
    

Molecular Weight8280.97 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0747

GRAVY Index0.50

Hydrophobic Moment 0.56

Boman Index0.14

Instability Index62.48

Aliphatic Index 110.54

Aromaticity 0.0811

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3064.74

LogP -23.01

H-bond Donors 116.0

H-bond Acceptors 114.0

Rotatable Bonds 268.0

Heavy Atoms 576.0

Ring Count 13.0

Amide Bonds 73.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0146990 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus asinus asinus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence