Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC119H190N40O32S

DescriptionStandard

        MRGIRGADFQAFQQARAVGLAGTFR
    

Molecular Weight2725.10 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.29

Charge Density (pH 7.0) 0.1001

GRAVY Index-0.10

Hydrophobic Moment 0.45

Boman Index-0.03

Instability Index-7.56

Aliphatic Index 62.80

Aromaticity 0.1200

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1196.12

LogP -13.41

H-bond Donors 43.0

H-bond Acceptors 36.0

Rotatable Bonds 91.0

Heavy Atoms 192.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329212 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEndostatin-derived peptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Anti-angiogenic Cytotoxic

TargetBxPC-3

Activity7 mg/kg/d

MethodInhibition

RECORD: Rec_0397821 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman endostatin [Animal]