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MYP_171785
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Basic Information
Glucagon like peptide 1 [7-36]
Binding / Molecular interaction ▸ Binding activity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
30 amino acids
C149H225N39O46
Standard
Sequence
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR
Physicochemical Analysis
3298.61 Da
5.53
-1.15
-1.41
-0.0382
-0.23
0.48
0.08
17.69
71.67
0.1333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1379.30
-13.40
49.0
46.0
108.0
234.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0277766 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antihyperglycemic Metabolic regulation
MS, ELISA
P700 plasma, in vitro; >345600 s
PaperDegradation and Stabilization of Peptide Hormones in Human Blood Specimens PMID26222180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26222180/
RECORD: Rec_0280413 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antidiabetic
ELISA
Mice (Subcutaneous injection), in vivo; 1200 s
PMID19531053 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19531053/
RECORD: Rec_0291389 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Biotinylation at Lys at 34th position
Bio-Activity Profile
Regulates blood glucose levels
RP-HPLC
Rat intestinal homogenate, in vitro; 80.4 s
PMID17904340 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17904340/
RECORD: Rec_0304972 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Insulinotropic
0.1 μM
ELISA
Rat blood plasma (Subcutaneous Injection), in vivo; 545.4 s
PMID15769092 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15769092/
RECORD: Rec_0305264 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Insulinotropic
0.00364±0.00025 μM
EC50
Rat intestinal fluid, in vitro; 30.6 s
PMID17904340 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17904340/
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