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MYP_171785
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Basic Information
Glucagon like peptide 1 [7-36]
Binding / Molecular interaction ▸ Binding activity
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
30 amino acids
C149H225N39O46
Standard
Sequence
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR
Physicochemical Analysis
3298.61 Da
5.53
-1.15
-1.41
-0.0382
-0.23
0.48
0.08
17.69
71.67
0.1333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1379.30
-13.40
49.0
46.0
108.0
234.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0247561 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Receptor-binding
0.02762±0.00213 μM
ELISA
Serum of rats (Subcutaneous injection), in vivo; <7200 s
PMID21664938 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21664938/
RECORD: Rec_0248292 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Human serum albumin
Bio-Activity Profile
Insulinotropic
100 μM
ELISA
Mouse plasma (Intraperitoneally administered), in vivo; 36000 s
PMID17986790 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17986790/
RECORD: Rec_0250314 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2753890 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2753890/
RECORD: Rec_0253078 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Pegylation on Lys34
Bio-Activity Profile
Insulinotropic
RP-HPLC
Rat liver homogenate, in vitro; 3720 s
PMID16586064 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16586064/
RECORD: Rec_0259050 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Glucagon
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone Metabolic
PMID2753890 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2753890/
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