MYP_171785
Glucagon like peptide 1 [7-36]
Binding / Molecular interaction
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Binding activity
Hormonal / Endocrine
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Hormone peptide
Metabolic
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Appetite and feeding regulation
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Metabolic
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Glucose metabolism
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Neurological / Signaling
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Neuromodulation
Neurological / Signaling
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Neuropeptide activity
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Neuropeptide
Regulatory peptide
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Biological modulation
Regulatory peptide
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Biological regulation
Regulatory peptide
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Cell-cell communication
Standard
30 amino acids
C149H225N39O46
Standard
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR
3298.61 Da
5.53
-1.15
-1.41
-0.0382
-0.23
0.48
0.08
17.69
71.67
0.1333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1379.30
-13.40
49.0
46.0
108.0
234.0
6.0
30.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0349569
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Counter-regulatory hormone
ELISA
Mouse plasma, in vivo; ~120 s
RECORD: Rec_0352424
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Insulinotropic
5600 μM
LC/MS equipped with a microbore C-18 HPLC
DPP IV, in vitro; 20880 s
RECORD: Rec_0364670
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
GLP-1
9606
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
X-1 = Lys- conjugated-7-hydroxyCoumarin maleimide
Bio-Activity Profile
Receptor-binding
EC50
Rat Plasma, in vitro; 42480 s
RECORD: Rec_0366290
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
None
Bio-Activity Profile
Insulinotropic
a receptor
0.0067 μM
IC50
Intraperitoneally administered to adult obese diabetic (ob /ob ) mice, in vivo; Completely resistant to degradation No units
RECORD: Rec_0375011
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Insulinotropic
RP-HPLC
Rat plasma, in vitro; 6840 s
Showing 5 records on this page · Page 10 of 12