MYP_171785
Basic Information
Glucagon like peptide 1 [7-36]
Binding / Molecular interaction Binding activity
Hormonal / Endocrine Hormone peptide
Metabolic
Metabolic Appetite and feeding regulation Feeding regulator
Metabolic Glucose metabolism Antidiabetic
Neurological / Signaling Neuromodulation
Neurological / Signaling Neuropeptide activity Neuropeptide
Regulatory peptide Biological modulation
Regulatory peptide Biological regulation
Regulatory peptide Cell-cell communication
Standard
30 amino acids
C149H225N39O46
Standard
Sequence
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR
Physicochemical Analysis
3298.61 Da
5.53
-1.15
-1.41
-0.0382
-0.23
0.48
0.08
17.69
71.67
0.1333
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1379.30
-13.40
49.0
46.0
108.0
234.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004055 VERIFIED: NO
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hormone
RECORD: Rec_0007484 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Biotinylation at Lys at 34th position
Bio-Activity Profile
Insulinotropic
0.00382±0.00032 μM
EC50
Rat intestinal fluid, in vitro; 70.2 s
RECORD: Rec_0016386 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Biotinylation at Lys at 34th and 26th position
Bio-Activity Profile
Regulates blood glucose levels
RP-HPLC
Rat intestinal fluid, in vitro; 260.4 s
RECORD: Rec_0024974 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antihyperglycemic Metabolic regulation
ESI-MS
Purified DPP IV, in vitro; >43200 s
RECORD: Rec_0034861 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Pegylation at N terminus His7
Bio-Activity Profile
Insulinotropic
RP-HPLC
Rat plasma, in vitro; 453600 s
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