Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC508H812N140O149S9

DescriptionStandard

        MSVMKPYLVTISILLILVRKTPGGLFRSQYGKSQEPWIPCQLYHGMCRHACRKNETQYLTCPDDQKCCLKFSVKIARSNNVKDYDPDSNLSVTNTSSYSKI
    

Molecular Weight11553.32 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)6.61

Net Charge (pH 7.4) 6.18

Charge Density (pH 7.0) 0.0655

GRAVY Index-0.40

Hydrophobic Moment 0.58

Boman Index-0.07

Instability Index36.71

Aliphatic Index 77.13

Aromaticity 0.0891

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4694.70

LogP -48.74

H-bond Donors 169.0

H-bond Acceptors 167.0

Rotatable Bonds 382.0

Heavy Atoms 806.0

Ring Count 18.0

Amide Bonds 110.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0076436 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhinus ursinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0223887 VERIFIED: NO

Provenance & Taxonomy

OrganismZalophus californianus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin