Peptide Database

Peptide NamePleiotrophin

Function Ontology

Binding / Molecular interaction ▸ Binding activity

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length136 amino acids

Chemical FormulaC658H1089N197O198S12

DescriptionStandard

        GKKEKPEKKVKKSDCGEWQWSVCVPTSGDCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRALHNAECQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
    

Molecular Weight15312.67 Da

Isoelectric Point (pI)9.64

Net Charge (pH 7.0)17.76

Net Charge (pH 7.4) 17.29

Charge Density (pH 7.0) 0.1306

GRAVY Index-1.19

Hydrophobic Moment 0.56

Boman Index-0.32

Instability Index22.71

Aliphatic Index 39.49

Aromaticity 0.0515

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 24115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6529.93

LogP -75.38

H-bond Donors 235.0

H-bond Acceptors 229.0

Rotatable Bonds 543.0

Heavy Atoms 1065.0

Ring Count 18.0

Amide Bonds 147.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390562 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Familypleiotrophin family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide15-44; 23-53; 30-57; 67-99; 77-109

Bio-Activity Profile

Function

Cytokine Growth factor pleiotrophin family Growth factor signaling Angiogenic Heparin-binding