Peptide Database

Peptide NameCliotide T2

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Insecticidal/Pest control ▸ Insecticidal activity

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC136H200N34O44S7

DescriptionStandard

        GDPFKCGESCFAGKCYTPGCTCEYPICMNN
    

Molecular Weight3239.70 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0432

GRAVY Index-0.26

Hydrophobic Moment 0.40

Boman Index0.08

Instability Index46.04

Aliphatic Index 16.33

Aromaticity 0.1333

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1232.12

LogP -14.75

H-bond Donors 46.0

H-bond Acceptors 50.0

Rotatable Bonds 98.0

Heavy Atoms 221.0

Ring Count 7.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0022648 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0369005 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

FamilyCyclotide

Tax ID43366

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Insecticidal Nematocidal Anthelmintic

TargetCaenorhabditis elegans