Peptide Database

Peptide NameDefensin-like peptide C-13326

Function Ontology

Antimicrobial

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC275H455N91O87S6

DescriptionStandard

        RPENLENVEDSGVVELVRHKRLSCLFENQAVSAIACGASCITRKGKRGGWCSNGVCRCTPN
    

Molecular Weight6620.50 Da

Isoelectric Point (pI)8.67

Net Charge (pH 7.0)2.80

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0459

GRAVY Index-0.35

Hydrophobic Moment 0.69

Boman Index-0.12

Instability Index61.06

Aliphatic Index 73.44

Aromaticity 0.0328

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2909.62

LogP -37.78

H-bond Donors 108.0

H-bond Acceptors 97.0

Rotatable Bonds 222.0

Heavy Atoms 459.0

Ring Count 6.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0381494 VERIFIED: YES

Provenance & Taxonomy

OrganismHermetia illucens [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAPD analysis reveals that this sequence is similar (39.39%) to Coprisin GRAVY: 0.35; mol Wt: 6620.594; mol formula: C275H461N86O87S6; mol ex coeff: 5925. Chemical modification: Disulfide bonds: C1-C4, C2-C6, and C3-C5

Bio-Activity Profile

Function

Antimicrobial Anti-inflammatory

TargetA. schubertii (MIC 125 ug/ml