‹ ›
MYP_171691
← PREVIOUS NEXT → BACK
Basic Information
Temporin-1DRa [Aib5]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
HFLGXLVNLAKKIL
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0021848 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 5
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25726
32 μM
MIC
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0032929 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 5
Bio-Activity Profile
Anticancer Cytotoxic
Human hepatocellular carcinoma HepG2
40 μM
LC50
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0061643 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
50 %
Hemolysis
PaperPubMed PMID: 17767978 PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0085533 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=AIB (Aminoisobutyric acid)
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
40 μM
LC50
PaperPubMed PMID: 17767978 PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
RECORD: Rec_0098561 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 5
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans ATCC 900280
8 μM
MIC
PMID17767978 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17767978/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2