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MYP_171627
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Basic Information
Phakellistatin 8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
10 amino acids
C61H90N10O12
Standard
Sequence
IFVLPPYIPP
Physicochemical Analysis
1155.43 Da
5.52
-0.24
-0.45
-0.0241
1.21
0.18
0.68
63.90
146.00
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
310.29
2.77
8.0
12.0
26.0
83.0
6.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035957 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
K562
0.29 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0112113 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0123476 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0137053 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: HCT 116
0.1 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
RECORD: Rec_0185501 VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
2.5 μM
IC50
PMID29893558 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29893558/
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